Showing posts with label disease. Show all posts
Showing posts with label disease. Show all posts

Tuesday, July 26, 2011

Roots Into the Future: New Project at 23andMe for African American, Black, and African research

Roots Into the Future:

10,000 FREE DNA Test kits for persons of Sub-Saharan African Ancestry

A recent article in Wired Magazine highlighted how the genome revolution has been skipping most people in the world: 96% of participants in recent genomic studies trace most of their ancestry to Europe. Why? Statistical analysis is simpler in groups tracing ancestry to just one continental region so fewer individuals are needed to make discoveries. Although African Americans typically trace about 20% of their ancestry to Europe, studies to verify previous findings in this population have not been done for many diseases. Our understanding of how DNA influences disease risk in people with mostly non-European ancestry has a lot of catching up to do.
23andMe hopes to bridge this growing divide through Roots into the Future, a research initiative addressing the needs of the African American community. Our partners in the research initiative include Dr. Henry Louis Gates and the W.E.B. Du Bois Institute at Harvard, as well as advisors from academia, industry and the 23andMe community. Our goal is to enroll 10,000 participants who self-identify as African American, Black, or African in order to rapidly accelerate genetic research in the African American community.

Continues at http://spittoon.23andme.com/2011/07/26/roots-into-the-future/

See the Roots Into the Future website: https://www.23andme.com/roots/

Thursday, October 14, 2010

Ancestry and Disease in the Age of Genomic Medicine

Review Article
Ancestry and Disease in the Age of Genomic Medicine
http://www.nejm.org/doi/full/10.1056/NEJMra0911564?query=TOC#t=articleTop

W. Gregory Feero, M.D., Ph.D., Editor, Alan E. Guttmacher, M.D., Editor

Ancestry and Disease in the Age of Genomic Medicine

Charles N. Rotimi, Ph.D., and Lynn B. Jorde, Ph.D.

N Engl J Med 2010; 363:1551-1558 October 14, 2010

Human genetic data are accumulating at an ever-increasing pace, and whole genome sequences of individuals from multiple populations are now publicly available.1-3 The growing inventory of human genetic variation is facilitating an understanding of why susceptibility to common diseases varies among individuals and populations. In addition, we are gaining insights that may improve the efficacy and safety of therapeutic drugs. Such knowledge is relevant to fundamental questions about our origins, differences, and similarities. Here, we provide a brief review of the current knowledge of human genetic variation and how it contributes to our understanding of human evolutionary history, group identity, and health disparities.