Sunday, March 10, 2013

Article Genetic Genealogy Comes of Age: Perspectives on the Use of Deep-Rooted Pedigrees in Human Population Genetics.

The full article is available:


Genetic Genealogy Comes of Age: Perspectives on the Use of Deep-Rooted Pedigrees in Human Population Genetics.

M H D Larmuseau, A Van Geystelen, M van Oven, R Decorte

UZ Leuven, Laboratory of Forensic Genetics and Molecular Archaeology, Leuven, Belgium; Department of Imaging and Pathology, KU Leuven, Forensic Medicine, Leuven, Belgium; KU Leuven, Department of Biology, Laboratory of Biodiversity and Evolutionary Genomics, Leuven, Belgium.
American Journal of Physical Anthropology (impact factor: 2.82). 02/2013; DOI:10.1002/ajpa.22233
Source: PubMed


In this article, we promote the implementation of extensive genealogical data in population genetic studies. Genealogical records can provide valuable information on the origin of DNA donors in a population genetic study, going beyond the commonly collected data such as residence, birthplace, language, and self-reported ethnicity. Recent studies demonstrated that extended genealogical data added to surname analysis can be crucial to detect signals of (past) population stratification and to interpret the population structure in a more objective manner. Moreover, when in-depth pedigree data are combined with haploid markers, it is even possible to disentangle signals of temporal differentiation within a population genetic structure during the last centuries. Obtaining genealogical data for all DNA donors in a population genetic study is a labor-intensive task but the vastly growing (genetic) genealogical databases, due to the broad interest of the public, are making this job more time-efficient if there is a guarantee for sufficient data quality. At the end, we discuss the advantages and pitfalls of using genealogy within sampling campaigns and we provide guidelines for future population genetic studies.

Am J Phys Anthropol, 2013. © 2013 Wiley Periodicals, Inc.

Tuesday, March 05, 2013

Sunday, March 03, 2013

FTDNA conversion to of Family Finder nearly completed

FTDNA has been converting Family Finder results to Build 37 of the reference human genome. Some problems were found with some previously run results and these are being rerun. In my case my Family Finder matches went down from 486 to 429. According to a notice from Bennet Greenspan and Max Blankfoeld they expect to complete the conversion on or about 5 March.