The On-line Journal of Genetics and Genealogy will highlight the connections between the science of Y and X chromosome, mitochondrial, and autosomal DNA analysis and genealogy. Reference will be made to scientific and genealogy articles which complement each other and advance the study of recent family history and ancient human migrations.
Thursday, August 09, 2018
Wednesday, November 22, 2017
Genetic Genealogy DNA test sales: FTDNA; 23andMe; AncestryDNA; MyHeritage
Family Tree DNA:
• Family Finder $59, usually $89
• Y-DNA $129, usually $169
• mt-DNA $169, usually $199
• Big Y $475 (includes Y-DNA test for 111 markers)
If you have already tested at FTDNA you will be receiving Discount Coupons that can further reduce these sale prices.
23andMe:
23andMe is charging $49.00 if you buy 2 Ancestry Service kits. The normal cost of the Ancestry Service is $99.00.
AncestryDNA:
AncestryDNA costs $79.00, a $20 discount from their regular price of $99.00. Rumor is that Ancestry will have a Black Friday price of $49.00.
MyHeritage:
This weekend, 24 Nov-27 Nov, MyHeritage is offering their normally priced $99.00 DNA test for $49.00 with free shipping for 3 or more kits.
Check all of the companies on Black Friday and Cyber Monday for possible lower costs.
Tuesday, April 25, 2017
DNA Day Sales at Family Tree DNA now through 27 April, 2017
Save on Family Finder, mtFull and Y-DNA tests April 20 - 27, 2017. The sale ends at 11:59pm CST Thursday April 27. And please share this with your relatives! If you have older relatives, please consider sponsoring their tests so that their DNA heritage can be discovered.
Questions? Please see Family Tree DNA or check your FTDNA homepage.
Thanks to Sandra Kidd.
Sunday, November 13, 2016
The following topics are covered:
- Introduction to the Conference;
- Dr Michael Hammer on "Ancient European DNA";
Announcement of the AncientOrigins result page
(non-European section is still under development);
- Presentation by Bill Griffith on his discovery that
his biological father was not the person who raised thought it was;
- Janine Cloud presented on "Personal Privacy in Public Projects";
- “Genographic Project Database: How Genetic Genealogists and Academics are working together”
by Dr. Miguel Vilar of the National Geographic Society;
- FTDNA Lab Manager Connie Bormans presented “What’s taking so long?!?!?! The Life Cycle of a DNA sample.”;
- Michael Sager presented on the FTDNA SNP Tree.
Check back tonight for the Sunday sessions.
Friday, November 27, 2015
FTDNA discounts through 31 December 2015
https://www.familytreedna.com/products.aspx
Enjoy!
Tuesday, October 08, 2013
New article on the genetic origins of Ashkenazi female lines
ARTICLE Received 11 Jul 2013 | Accepted 4 Sep 2013 | Published 8 Oct 2013
A substantial prehistoric European ancestry amongst Ashkenazi maternal lineages
Marta D. Costa [1,2,*], Joana B. Pereira[1,2,*], Maria Pala [3], Vero´nica Fernandes [1,2], Anna Olivieri [4], Alessandro Achilli [5], Ugo A. Perego [4,6], Sergei Rychkov [7], Oksana Naumova[7], Jirˇi Hatina[8], Scott R. Woodward [6,9], Ken Khong Eng [1,10],
Vincent Macaulay [11], Martin Carr [3], Pedro Soares [2], Luı´sa Pereira [2,12] & Martin B. Richards [1,3]
The origins of Ashkenazi Jews remain highly controversial. Like Judaism, mitochondrial DNA
is passed along the maternal line. Its variation in the Ashkenazim is highly
distinctive, with four major and numerous minor founders. However, due to their rarity in the
general population, these founders have been difficult to trace to a source. Here we show that
all four major founders, ~40% of Ashkenazi mtDNA variation, have ancestry in prehistoric
Europe, rather than the Near East or Caucasus. Furthermore, most of the remaining minor
founders share a similar deep European ancestry. Thus the great majority of Ashkenazi
maternal lineages were not brought from the Levant, as commonly supposed, nor recruited in
the Caucasus, as sometimes suggested, but assimilated within Europe. These results point to
a significant role for the conversion of women in the formation of Ashkenazi communities,
and provide the foundation for a detailed reconstruction of Ashkenazi genealogical history.
- Institute of Integrative and Comparative Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, UK.
- IPATIMUP (Instituto de Patologia e
Imunologia Molecular da Universidade do Porto), Porto 4200-465, Portugal.
- School of Applied Sciences, University of Huddersfield, Queensgate,
Huddersfield HD1 3DH, UK.
- Dipartimento di Biologia e Biotecnologie, Universita` di Pavia, Pavia 27100, Italy.
- Dipartimento di Chimica, Biologia e
Biotecnologie, Universita` di Perugia, Perugia 06123, Italy.
- Sorenson Molecular Genealogy Foundation, Salt Lake City, Utah 84115, USA.
- Vavilov Institute of
General Genetics, Moscow 119991, Russia.
- Charles University, Medical Faculty in Pilsen, Institute of Biology, CZ-301 66 Pilsen, Czech Republic.
- Ancestry,Provo, Utah 84604, USA.
- Centre for Global Archaeological Research, Universiti Sains Malaysia, 11800 USM Penang, Malaysia.
- School of Mathematics
and Statistics, University of Glasgow, Glasgow G12 8QQ, UK.
- Faculdade de Medicina da Universidade do Porto, Porto 4200-319, Portugal.
- These authors contributed equally to this work. Correspondence and requests for materials should be addressed to M.B.R. (email: m.b.richards@hud.ac.uk).
Thursday, February 07, 2013
James Lick on analyzing the mtDNA of Richard III with very little data [UPDATED]
I thought it would be fun to try analyzing the mtDNA sequence of the presumed Richard III skeleton using my mthap program to see what it comes up with.
Unfortunately, only a 53bp fragment of the ~16569bp mtDNA sequence has been released so far, via this image on the University of Leicester web site [see here for the rest]
(Please note that this is not meant to cast doubt on the identification. It is merely to show how much objective data we can determine based on the currently released information.)
UPDATE
More detail on Richard III's probable mtDNA:
Tuesday, November 13, 2012
FTDNA Holiday sale: Now till 31 Dec 2012
New Kits Current Price SALE PRICE Y-DNA 37 $169 $119 Y-DNA 67 $268 $199 mtDNAPlus $159 $139 mtFullSequence (FMS) $299 $199 SuperDNA (Y-DNA 67 and mtFullSequence) $548 $398 Family Finder $289 $199 Family Finder + mtDNAPlus $438 $318 Family Finder + mtFullSequence $559 $398 Family Finder + Y-DNA 37 $438 $318 Comprehensive (FF + FMS + Y-67) $837 $597
Upgrades Current Price SALE PRICE Y-Refine 12-25 Marker $59 $35 Y-Refine 12-37 Marker $109 $69 Y-Refine 12-67 Marker $199 $148 Y-Refine 25-37 Marker $59 $35 Y-Refine 25-67 Marker $159 $114 Y-Refine 37-67 Marker $109 $79 Y-Refine 37-111 Marker $220 $188 Y-Refine 67-111 Marker $129 $109 mtHVR1toMega $269 $179 mtHVR2toMega $239 $179 mtFullSequence Add-on $289 $199
To order this special offer, log in to your personal page and click on the Order An Upgrade button in the upper right corner. A link to the login page is provided below. ALL ORDERS MUST BE PLACED AND PAID FOR BY MONDAY, DECEMBER 31, 2012 11:59:00 PM CST TO RECEIVE THE SALE PRICES.
Log In to Order an Upgrade.
Click Here to Order a New Kit.
As always, we appreciate your continued support.
Family Tree DNA
www.familytreedna.com
"History Unearthed Daily"
Sunday, November 04, 2012
Abstract from American Society of Human Genetics meeting session
S. Wells1, E. Greenspan2, S. Staats2, T. Krahn2, C. Tyler-Smith3, Y. Xue3, S. Tofanelli4, P. Francalacci5, F. Cucca6, L. Pagani7, L. Jin8, H. Li8, T. G. Schurr9, J. B. Gaieski9, C. Melendez9, M. G. Vilar9, A. C. Owings9, R. Gomez10, R. Fujita11, F. Santos12, D. Comas13, O. Balanovsky14, E. Balanovska14, P. Zalloua15, H. Soodyall16, R. Pitchappan17, G. Arun Kumar17, M. F. Hammer18, B. Greenspan2, E. Elhaik19
1) Mission Programs, National Geographic Society, Washington, DC; 2) Family Tree DNA, Houston, TX; 3) Wellcome Trust Sanger Institute, Hinxton, UK; 4) University of Pisa, Italy; 5) University of Sassari, Italy; 6) National Research Council, Monserrato, Italy; 7) University of Cambridge, UK; 8) Fudan University, Shanghai, China; 9) University of Pennsylvania, Philadelphia, PA; 10) CINVESTAV, Mexico City, Mexico; 11) University of San Martin de Porres, Lima, Peru; 12) Federal University of Minas Gerais (UFMG), Belo Horizonte, Brazil; 13) Pompeu Fabra University, Barcelona, Spain; 14) Russian Academy of Medical Sciences, Moscow, Russia; 15) Lebanese American University, Byblos, Lebanon; 16) University of the Witwatersrand, Johannesburg, South Africa; 17) Chettinad Academy of Research and Education, Chennai, India; 18) University of Arizona, Tucson, AZ; 19) Johns Hopkins University, Baltimore, MD.
Background: The Genographic Project is an international effort aimed at charting human history using genetic data. The project is non-profit and non-medical, and through the sale of its public participation kits it supports cultural preservation efforts in indigenous and traditional communities. To extend our knowledge of the human journey, interbreeding with ancient hominins, and modern human demographic history, we designed a genotyping chip optimized for genetic anthropology research. Methods: Our goal was to design, produce, and validate a SNP array dedicated to genetic anthropology. The GenoChip is an Illumina HD iSelect genotyping bead array with over 130,000 highly informative autosomal and X-chromosomal SNPs ascertained from over 450 worldwide populations, ~13,000 Y-chromosomal SNPs, and ~3,000 mtDNA SNPs. To determine the extent of gene flow from archaic hominins to modern humans, we included over 25,000 SNPs from candidate regions of interbreeding between extinct hominins (Neanderthal and Denisovan) and modern humans. To avoid any inadvertent medical testing we filtered out all SNPs that have known or suspected health or functional associations. We validated the chip by genotyping over 1,000 samples from 1000 Genomes, Family Tree DNA, and Genographic Project populations. Results: The concordance between the GenoChip and the 1000 Genomes data was over 99.5%. The GenoChip has a SNP density of approximately (1/100,000) bases over 92% of the human genome and is highly compatible with Illumina and Affymetrix commercial platforms. The ~10,000 novel Y SNPs included on the chip have greatly refined our understanding of the Y-chromosome phylogenetic tree. By including Y and mtDNA SNPs on an unprecedented scale, the GenoChip is able to delineate extremely detailed human migratory paths. The autosomal and X-chromosomal markers included on the GenoChip have revealed novel patterns of ancestry that shed a detailed new light on human history. Interbreeding analysis with extinct hominids confirmed some previous reports and allowed us to describe the modern geographical distribution of these markers in detail. Conclusions: The GenoChip is the first genotyping chip completely dedicated to genetic anthropology with no known medically relevant markers. We anticipate that the large-scale application of the GenoChip using the Genographic Project’s diverse sample collection will provide new insights into genetic anthropology and human history.
You may contact the first author (during and after the meeting) at spwells@ngs.org
Thursday, August 23, 2012
FTDNA Super Summer Sale
| Dear Family Tree DNA Project Administrator, | |||||||||
|
It seems that every time we run a super sale that a few people email us days later that they were traveling, sick or just hadn't looked at their emails in time, so for all of you who have wanted to entice a friend, neighbor or reluctant relative to get involved in Genetic Genealogy here's one more opportunity, but it will last for only 72 hours. These are the only two options on sale, and they are geared specifically for newcomers. This sale will end on Saturday, August 25, at 11:59PM. | |||||||||
| |||||||||
|
As with all promotions, orders need to be
placed by the end of the sale and payment must be
made by end of this sale. Learn More |
Wednesday, July 11, 2012
GeneTree Closing Notice
You may have recently heard the exciting news that GeneTree has been acquired by AncestryDNA™ ( http://corporate.ancestry.com/press/press-releases/2012/05/ancestry.com-dna-launches/ ). As we redirect our efforts to the integration with AncestryDNA it will be necessary to discontinue the GeneTree.com website. However, as a valued GeneTree customer, you will be able to access GeneTree.com through the rest of this year, until January 1, 2013. Following this date, access to your account will no longer be available through the GeneTree site, so we recommend that you download your DNA results and pedigree data while the site is still available.
If you’d like to learn more about how to download and continue using your information and family tree outside of GeneTree, see click here To help answer some frequently asked questions, please visit our FAQs. We greatly appreciate you being a part of GeneTree and hope that you continue with your genetic genealogy and family history research.
Sincerely, The GeneTree Team
GeneTree Logo
http://genetree.com/ | genetreesupport@ancestry.com | +1.800.694.6805 | FAQ | Privacy
2480 South Main Street, Suite 200 Salt Lake City, UT 84115 USA
Monday, July 09, 2012
Family Tree DNA's Sizzling summer Promotion
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| Best Regards, Bennett Greenspan President Family Tree DNA www.familytreedna.com "History Unearthed Daily" |
Wednesday, June 13, 2012
Genetic Genealogy course from the National Genealogical Society
What’s Happening at the
National Genealogic al Society, 13 June 2012:
· human chromosomes and how the Y chromosome is inherited;
· the two types of DNA markers used in genetic genealogy;
· haplotypes and haplogroups;
· evaluation of a Y chromosome surname project and a discussion on how to evaluate the test results of the participants; and
· the structure of the mitochondrial DNA molecule, how it is inherited, and how it can be used in genealogy.
Please visit the course web page at http://www.ngsgenealogy.org/
Saturday, June 02, 2012
Status of the Sorenson Molecular Genealogy Foundation, SMGF,genetic genealogy DNA Databases and GeneTree
Hello Steven,
Yes, the databases have been transferred to Ancestry.com. GeneTree will not be continuing; they have stopped taking orders and in the near future www.genetree.com will be taken down. There are not plans to automatically 'convert' GeneTree accounts into Ancestry.com accounts, so GeneTree customers will need to move their information over to Ancestry on an individual basis.
As far as the autosomal database is concerned, our autosomal tests were generated with older technology, making them incompatible with current industry standards. Therefore, they are not included in the autosomal service offered by AncestryDNA. We also don't plan on making them available via smgf.org.
Best regards,
SMGF
As of today, 1 June 2012, the Y DNA and mtDNA databases are still available at the SMGF site: http://smgf.org/ If you have tested I suggest you go and download your results and your matches. It is my understanding that people will be able to remove their results from the Ancestry.com databases if they so desire.
Tuesday, August 02, 2011
Comparison of 23andme Relative Finder, Ancestry Finder and FTDNA Family Finder results
I'll repeat a post I made at 23andme on comparing success rates at both:
======================================
Colonial American ancestry: Jamestown, Boston, Cambridge, Hartford, New Haven Colony, New Amsterdam, New Sweden, New Jersey, Pennsylvania. Then spread out to North Carolina, South Carolina, both pre-Rev War; then Tennessee and Kentucky, post-Rev War.
- at 23andme I have 1050 RF matches and have confirmed 7 of those.
- at FTDNA I have 175 FF matches and have confirmed 10 of those.
- Two of my confirmed matches have tested both 23andme RF and FTDNA FF.
- I have 20 separate X Chromosome matches in RF and AF. That counts repeated people only once.
- I have no immediate matches at FTDNA. I have 54 close matches and 121 speculative matches. My closest confirmed matches are two 4th cousins.
- I have two known 1st cousins at 23andme and two unresponsive 2nd cousins. My closest confirmed match at 23andme is with a 3rd cousin once removed and her daughter.
=======================
If you haven't done any tests I recommend starting at 23andme and then, when FTDNA opens the program, transferring your results to FTDNA. That way you get genealogical matches from both companies, you get mtDNA haplogroup and if a male, Y DNA haplogroup, and X chromosome matches at 23andme plus health info.
At FTDNA you get genealogy matches and when they get it ready, X chromosome matches. You have to pay separately for the Y DNA haplotype and haplogroup and the same for mtDNA. So from a cost perspective it is lower cost to start at 23andme and transfer to FTDNA UNLESS you also want detailed Y DNA /mtDNA readings.
Wednesday, June 15, 2011
FTDNA Summer DNA tests Sale
You must already be a customer of FTDNA to get these UPGRADE prices!
Family Tree DNA
Dear Project Administrator,
Since last summer's upgrade sale was such huge success, we thought we'd repeat history! Project Administrators like you played a very important role in last year's success by broadcasting the sale to project members. As your project members upgrade, the resolution of results and comparisons we provide greatly improves. So, please spread the word and we'll make this year's upgrade sale even bigger!
From June 15, 2011 through June 22, 2011, we will reduce the following prices.
Summer Upgrade Sale
Family Finder Was $289 Now $199
Y-DNA 12 to 25 Was $49 Now $35
Y-DNA 12 to 37 Was $99 Now $69
Y-DNA 12 to 67 Was $189 Now $148
Y-DNA 25 to 37 Was $49 Now $35
Y-DNA 25 to 67 Was $148 Now $114
Y-DNA 37 to 67 Was $99 Now $79
mt to FMS Was $269 Now $229
mtPlus to FMS Was $239 Now $199
To order an upgrade at these special prices your members can log into their personal pages with their kit number and password. Click on the "Special Offers" link found on the left-hand navigation bar. ALL ORDERS MUST BE PLACED AND PAID FOR BY MIDNIGHT, JUNE 22, 2011, TO RECEIVE THE SALE PRICE.
Family Tree DNA
© 2011 Genealogy by Genetics.
Monday, May 30, 2011
Analysing 23andMe Relative Finder results: Always take a second look.
See corrected text below: NOT my Father's mtDNA haplotype.
Several months ago I got a a 22cM 23andMe Relative Finder match with A. Her surname was one in my paternal grandmother's ancestry. She was a predicted 4th cousin with a range of 3rd to 7th. We compared ancestry charts and determined we shared two lines on her Father's side. We were both half 5th cousins once removed and half 6th cousins on that surname. I was descended from a husband and one wife and she was descended from the other wife on two lines.
This week I noticed her father's results had arrived and I did not have a match with him. Since a 22cM match seemed too large to be Identical by State and/or fit into those situations where one has a match with a child but not a parent, I looked at the link to her updated Ancestry tree and found that she and I had a 5th cousin relationship on her Mother's side also through my paternal grandmother.
In this case she was a direct female line descendant of my Father's direct female line ancestor, so her mtDNA was the same as my paternal grandmother and my Father. This filled in one of my missing mtDNA haplogroups and indicated that the first relationships found probably were not the ones that passed on the genetic match.
We do share some other surnames but can't find a relationship yet on those other lines. Even if there are relationships on the other lines they would be further back than the closest one we now have.
Please let me know of any problems with my analysis.
Sunday, April 17, 2011
DNA haplogroups of European Royalty
The following list of DNA haplogroups of European Royalty is found on the EUpedia site: http://www.eupedia.com/forum/showthread.php?25236-Haplogroups-of-European-kings-and-queens
I cannot vouch for the accuracy of the posting, but it may be of interest to genetic genealogists.
Thursday, April 14, 2011
Family Tree DNA 36 hour sale on DNA tests
From the FTDNA Facebook Page:
Coupon Code: DNADAY2011
Share · Public Event
http://www.familytreedna.com
Created By Family Tree DNA
DNA Day is April 15th! Starting at 12:00 PM on April 14th, join the celebration!
New customers: Y-DNA12……. $59 Y-DNA37……. $129 ...mtDNA………. $59 Family Finder… $199 Family Finder + Y-DNA12….. $258 Family Finder + mtDNA…….. $258 Family Finder + mtFullSequence + Y-DNA67 …. $657
Upgrades: Y-DNA12 add-on ….. $59 Y-DNA12 to 37…….. $69 Y-DNA37 to 67…….. $79 Y-DNA12 to 67…….. $148 mtDNA add-on …….. $59 mtFull Sequence upgrade ….. $199
To take advantage of these promotional prices use the coupon code: DNADAY2011
The coupon code will expire on Friday at midnight (CST).
Please note, the Y-DNA67 to 111 upgrade will remain at the introductory rate of $101 (no coupon necessary) until the end of this promotion. The price will be $129 going forward.
Payment must be received at the time of the order. Valid only on products listed. No substitutions. This promotion was announced in advance, therefore no adjustments will be made on previous purchases. Offer valid from 12:00 PM CST on Thursday, April 14, until 11:59 PM CST on April 15, 2011.
This promotion is not valid in combination with any other promotions. Family Tree DNA reserves the right to cancel any order due to unauthorized or ineligible use of discounts and to modify or cancel these promotional discounts due to system error or unforeseen problems. Subject to change without notice.
Sunday, April 10, 2011
Family Tree DNA switches autosomal DNA tests to the Illumina chip
In February FTDNA announced that they were switching to the Illumina OMNI test chip for their Family Finder autosomal DNA test. Since then people have been gradually getting their test results from the new chip. At this time I have 122 matches from the old Affimatrix chip and 110 from the Illumina chip. They are not all the same and I will be comparing the results from each chip.
In the past I have advised people to do their first autosomal DNA test at 23andme.com since they had a lower cost and they compared the X chromosome, which FTDNA does not currently do. In addition, males got their Y DNA haplogroup and their mtDNA haplogroup. Females got the mtDNA haplogroup. Since FTDNA had announced that they would compare 23andme results to FTDNA Family Finder results, this seemed to be the most cost-effective testing protocol to follow. The switch by FTDNA should make the comparison of results much easier since 23andme also uses an Illumina test chip.

